在阿拉比多普西斯中,强大的器官大小主要由细胞生长而不是细胞分裂模式来决定
Isabella Burda1,2,3, Fridtjof Brauns4, Frances K Clark1,2,3
1Genetics, Genomics, and Development Graduate Program, Cornell University, Ithaca, NY 14850, USA.
Development (Cambridge, England)
|September 26, 2024
概括
强大的器官发育依赖于平均细胞生长波动. 细胞分裂的数量不会影响这个平均值,但Arabidopsis thaliana分的相关生长变化会破坏它,导致形状变化.
科学领域:
- 植物生物学 植物生物学
- 发育生物学是发展生物学.
- 细胞形态发生是细胞形态发生.
背景情况:
- 器官的大小和形状在物种内部具有很高的复制性.
- 阿拉比多普西斯·塔利安娜的体表现出一致的尺寸和形状,显示出强大的发育.
- 由于内在和外在的噪音,局部细胞生长是异质的.
研究的目的:
- 调查在Arabidopsis thaliana体中稳健的器官形状确定背后的机制.
- 确定细胞分裂数和细胞生长变异性在器官形态发生过程中的作用.
- 阐明细胞生长中的空间和时间相关性如何影响器官形状的一致性.
主要方法:
- 在线成像和量化Arabidopsis thaliana分离体发育.
- 对细胞分裂数量改变的突变物 (lgo突变物,LGO过度表达) 的分析.
- 对细胞生长变异性改变的突变物 (ftsh4) 和双重突变物进行分析.
主要成果:
- 细胞分裂数量的变化并没有改变整体分离体生长模式.
- 由于相关的细胞生长,ftsh4突变体表现出累积的过度和不足生长斑块.
- 在ftsh4突变体中,相关的生长波动损害了平均值,导致器官形状变异性增加.
结论:
- 细胞分裂的数量不是平均细胞生长和保持强大的器官形态发生的关键因素.
- 相关的细胞生长波动损害了平均化过程,破坏了强壮的器官形状.
- 这项研究在体内证明了与保持器官形状一致性无关的细胞生长的重要性.
关键词:
阿拉比多普西斯塔利亚纳.在FTSH4中使用.经批准的重复复制.巨细胞是巨大的细胞.这是一个LGO LGO.形态发生 形态发生 形态发生塞帕尔·塞帕尔 (Sepalpal Sepal) 是一个独立的语言.时间空间的平均值.更多相关视频
09:27High Resolution Quantification of Crystalline Cellulose Accumulation in Arabidopsis Roots to Monitor Tissue-specific Cell Wall Modifications
Published on: May 10, 2016
8.1K
07:52Live Cell Imaging of Microtubule Cytoskeleton and Micromechanical Manipulation of the Arabidopsis Shoot Apical Meristem
Published on: May 23, 2020
5.3K
相关概念视频
02:36Cells Coordinate Growth and Proliferation
4.5K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
4.5K
02:19Morphogenesis
27.7K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
27.7K
01:25Cell Signaling in Plants
5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K
01:28The Cell Cycle Control System
2.7K
The cell cycle regulation directs how a cell proceeds from one phase to the next and begins mitosis. The cell cycle control system includes intracellular regulatory molecules and external triggers. They provide "stop" or "advance" signals and operate at specific cell cycle stages termed checkpoints to ensure that a particular process is completed before the cell advances to the next phase.
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
2.7K
03:02Primary and Secondary Growth in Roots and Shoots
57.0K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
57.0K
02:36Meristems and Plant Growth
45.7K
Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
45.7K