使用双标记水方法测量与日本老年人水需求相关的因素的决定因素
Daiki Watanabe1,2,3, Tsukasa Yoshida2,3, Hinako Nanri2
1Faculty of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa-City, Saitama359-1192, Japan.
Public health nutrition
|September 26, 2024
概括
这项研究开发了一种新的方程,用于预测使用生物标志物校准的老年人每日水循环 (WT) 和预先形成的水 (PW). 这些发现为评估老年人水分状况提供了更好的方法.
科学领域:
- 老年学和营养科学研究
- 生物标志物开发和验证
背景情况:
- 水是生命和健康的关键营养素,需要对水循环 (WT) 和预制水 (PW) 进行准确的评估.
- 评估水分状态的现有方法可能有限,特别是在老年人群中.
研究的目的:
- 开发和验证一个生物标志物校准方程,用于预测WT和PW.
- 使用双标记水 (DLW) 方法来准确测量水动力学.
- 确定影响老年人水需求的关键因素.
主要方法:
- 一项涉及141名年龄≥65岁的参与者的横截面研究,来自京都-卡梅奥卡研究.
- 参与者被分为开发 (n=71) 和验证 (n=70) 队列.
- 使用DLW方法测量WT和PW;使用问卷数据 (饮食摄入量,个人特征) 的多变量渐进回归开发了预测方程,并根据DLW测量进行了验证.
主要成果:
- 中位数WT和PW分别为2.81 L/d和2.28 L/d.
- 多变量模型适度预测WT (R2=0.652) 和PW (R2=0.623) 使用身高,体重和饮料中的液体摄入等变量.
- 预测的WT (r=0.527) 和PW (r=0.477) 与DLW测量值呈现正相关性.
结论:
- 该研究确定了与老年人水需求相关的关键因素.
- 建立了一种新的方法方法来校准自我报告的饮食摄入数据,使用水消耗的生物标志物.
- 开发的方程为估计水循环和预制水提供了实用工具,有助于对水分的评估.
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