出院后的死亡率在一个因厌食症精神病住院的队列中
Scott B Patten1, Gina Dimitropoulos2, Julia Hews-Girard3
1Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
The International journal of eating disorders
|September 26, 2024
概括
精神病医院住院后的死亡率在厌食症 (AN) 和其他精神病患者之间是相似的. 然而,AN在AN队列中是一个重要的潜在死亡原因,这表明需要专门的预防策略.
科学领域:
- 精神病学和公共卫生研究研究 精神病学和公共卫生研究
- 临床流行病学临床流行病学
- 死亡率研究 死亡率研究
背景情况:
- 了解住院后的死亡率对于有效的患者护理和资源配置至关重要.
- 神经性厌食症 (AN) 是一种严重的精神疾病,与严重的健康风险有关,包括过早死亡.
- 对抗其他精神疾病的死亡率的比较分析对于有针对性的干预措施至关重要.
研究的目的:
- 为了比较精神病医院住院后出院的患者的死亡率,有或没有被诊断为神经性厌食症 (AN).
- 为了确定AN队列中死亡的潜在原因.
- 为制定AN专业预防策略提供信息.
主要方法:
- 利用加拿大大规模的精神病医院住院数据集 (n=130万) 从2006年到2021年.
- 使用ICD-10代码 (F50.0,F50.1) 确定了神经性厌食症 (AN) 的病例.
- 将住院数据与生命统计数据联系起来,并使用Cox比例危险模型和竞争性因果回归来分析死亡率.
主要成果:
- 经过调整后的分析显示,AN与其他精神病学队列之间的总死亡率没有显著差异 (HR=1.04,p=0.644).
- 在AN组中,精神疾病占死亡人数的25%,而AN本身是所有死亡人数的22%的根本原因.
- 相比之下,非AN精神病队伍中只有8%的死亡被归因于精神障碍.
结论:
- 虽然整体死亡风险与其他精神疾病相比,神经性厌食症 (AN) 是导致死亡的主要直接因素.
- 精神病患者群体的标准死亡率预防策略 (例如,管理代谢和生活方式因素) 可能对AN不足.
- 专业的预防性干预可能是必要的,以减少早逝的死亡率,特别是在患有AN的个体.
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