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Updated: Jun 12, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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通过双调节p53,SNP赋予LACTB瘤基因样功能,并通过双调节p53加速瘤进展

Guanyu Huang1,2, Jiajun Zhang1,2, Yu Xu1,2

  • 1Department of Musculoskeletal Oncology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 26, 2024
PubMed
概括

在骨髓瘤中,LactB突变 (M5L+R469K) 通过改变p53调节来促进癌症的进展. 克拉夫酸抑制了这种突变蛋白,为骨髓瘤提供了潜在的治疗策略.

关键词:
据说,LACTB 是一个有趣的动物.克拉夫兰酸酸是什么?骨质肉瘤是骨质肉瘤的一种疾病.在 p53 里,p53 是一个 p53 号码.

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