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基因组编辑技术的研究支持和过渡到临床试验的研究特征
Riya Mohan1, Susanne B Haga1,2
1Trinity College of Arts and Sciences, Duke University, Durham, North Carolina, USA.
The CRISPR journal
|September 26, 2024
概括
联邦对基因组编辑研究的资金急剧增加,平均年增长率为40%,自2020年以来,临床试验的数量大幅增加. 这凸显了基因编辑技术的快速扩张.
科学领域:
- 生物技术是生物技术.
- 遗传学 是一个遗传学.
- 医学研究 医学研究
背景情况:
- 基因组编辑技术是越来越重要的研究工具.
- 评估联邦资助趋势对于了解研究势头至关重要.
研究的目的:
- 分析基因组编辑项目的联邦资金增长率.
- 确定基因组编辑研究奖项和临床试验启动的趋势.
主要方法:
- 利用了来自NIH RePORTER和Clinicaltrials.gov (1977-2023) 的公开数据.
- 分析了6111个奖项,重点关注增长率和资金分配.
主要成果:
- 基因组编辑奖项的平均增长率为40% (2008-2022年),在2017-2018年期间出现了显著的激增.
- 国家癌症研究所率先提供资金,占奖项的20%.
- 75%的基因组编辑临床试验始于2020年或之后.
结论:
- 基因组编辑研究正在经历跨科学学科的快速,广泛增长.
- 越来越多的临床试验表明,基因编辑工具将转化为治疗应用.
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