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Updated: Jun 12, 2025

Overexpressing Long Noncoding RNAs Using Gene-activating CRISPR
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Published on: March 1, 2019

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外源的Janus 激酶617 Codon 影响小非编码RNA和 Ba/F3 细胞中的基因表达

Yi-Yang Chen1, Ying-Hsuan Wang1,2, Chih-Cheng Chen1,2

  • 1Division of Hematology and Oncology, Chang Gung Memorial Hospital, Chiayi, Taiwan.

Journal of physiological investigation
|September 26, 2024
PubMed
概括

骨髓增殖性瘤 (MPNs) 中的JAK2V617F突变可以重新安排表观基因组,影响微RNA和PIWI相互作用RNA表达. 这项研究阐明了这种突变如何通过JAK-STAT途径驱动MPN转换.

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