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多发性硬化症中神经精神症状和认知之间的关系:系统性审查
Johanna Helminen1, Mervi Jehkonen1,2
1Faculty of Social Sciences, Tampere University, Tampere, Finland.
Applied neuropsychology. Adult
|September 26, 2024
概括
神经精神症状,特别是抑郁和冷漠,与多发性硬化症 (MS) 患者的认知能力下降有关. 本系统综述强调了这些症状对成年多发性硬化症患者各种认知功能的影响.
科学领域:
- 神经学 神经学
- 神经心理学 神经心理学
- 精神病学是一个精神病学.
背景情况:
- 关于多发性硬化症 (MS) 中神经精神病症状和认知功能之间的关联,存在不同的发现.
- 了解这种关系对于管理MS患者的整体健康和生活质量至关重要.
研究的目的:
- 在成年多发性硬化患者中,系统地审查有关神经精神症状和认知领域之间的关系的现有证据.
- 巩固发现并确定特定症状和认知障碍之间的一致模式.
主要方法:
- 在主要数据库 (Ovid Medline,PsycInfo,Scopus,Web of Science) 进行了全面的文献搜索.
- 从4,216个初始记录中确定了37项研究,符合系统审查的纳入标准.
主要成果:
- 较高的抑郁症状与处理速度,口头记忆,执行功能,视觉空间功能和注意力的缺陷相关.
- 漠不关心与执行功能,视觉空间功能,视觉记忆,工作记忆和处理速度受损有着强烈的关联.
- 焦虑症状与认知功能没有一致的关系,对视觉记忆缺陷的联系的支持很小.
结论:
- 神经精神症状的增加,特别是抑郁和冷漠,与多发性硬化症的认知功能障碍有关.
- 这些发现强调了评估和解决神经精神病症状在MS患者临床管理中的重要性.
- 结果可以为多发性硬化症患者的临床检查和治疗计划提供信息.
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