免疫介导炎症疾病患者的HPV感染和预防:一个范围审查
Tiphaine Goulenok1, Karim Sacré
1From the Department of Internal Medicine, Bichat-Claude Bernard Hospital, Assistance Publique Hôpitaux de Paris, Université Paris Cité, Paris, France.
概括
人类乳头瘤病毒 (HPV) 疫苗接种和查对于患有免疫媒介炎症疾病的人来说至关重要. 鼓励HPV疫苗接种和实施子宫癌查可以显著降低这一脆弱人群的癌症风险.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 人类乳头瘤病毒 (HPV) 感染是男性和女性各种癌症的主要原因.
- 免疫抑制在患有免疫媒介性炎症性疾病 (IMIDs) 的患者,如系统性红斑狼,提高了持久性HPV感染和癌前病变的风险.
研究的目的:
- 要突出患有IMIDs的患者患有HPV相关癌症的风险增加.
- 强调疫苗接种和查在管理HPV在这一群体中的重要性.
主要方法:
- 对IMID患者HPV感染的当前文献的综述.
- 分析现有的管理策略,包括疫苗接种和查指南.
主要成果:
- 在IMID患者中,HPV疫苗接种是安全有效的,但覆盖率很低.
- 建议对这一群体进行宫癌查,与其他免疫抑制个体的指导方针保持一致.
结论:
- 疫苗接种和查是IMID患者HPV的基本管理策略.
- 增加HPV疫苗接种率和更广泛地实施宫癌查是必要的.
- 像追赶疫苗接种,自取样本HPV测试和治疗性疫苗等新兴选择需要考虑.
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