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Updated: Jun 12, 2025

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
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A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

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协同的赛莱科克西布和二甲基-赛莱科克西布组合通过多种机制阻断子宫癌的生长

Diana Xochiquetzal Robledo-Cadena1,2, Silvia Cecilia Pacheco-Velázquez3, Jorge Luis Vargas-Navarro4

  • 1Departamento de Bioquímica, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México.

PloS one
|September 26, 2024
PubMed
概括

结合化疗的赛莱科西布 (CXB) 或二甲基-赛莱科西布 (DMC) 通过阻断能量通路和ATP生产,协同抑制宫癌细胞的增殖. 这种组合选择性地向癌细胞,为宫癌治疗提供了一个有前途的策略.

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