在使用抗抑郁药的患者中,睡眠中肢体的周期性运动
Hossam Marey1, Andrew Chai2, Andras Bikov3
1Pennine Care NHS Foundation Trust, Manchester, United Kingdom.
Sleep medicine reviews
|September 26, 2024
概括
抑郁症和睡眠中的肢体周期性运动往往同时发生. 抗抑郁药可以恶化这些运动,影响睡眠质量,但效果因药物机制而异.
科学领域:
- 神经科学是一个神经科学.
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 抑郁症和睡眠中的四肢周期性运动 (PLMS) 是普遍存在的,经常伴随的疾病.
- 众所周知,抗抑郁药可加剧PLMS,对睡眠质量和白天功能产生负面影响.
研究的目的:
- 审查PLMS背后的机制.
- 评估各种抗抑郁药对PLMS的影响.
- 讨论临床影响和未来的研究方向.
主要方法:
- 关于PLMS机制的综合文献审查.
- 对抗抑郁药诱导的PLMS研究的分析.
- 在PLMS中神经递质作用的合成.
主要成果:
- 抗抑郁药对PLMS的影响依赖于机制.
- 神经递质的改变在PLMS中起着关键作用.
- 特定的抗抑郁药类对PLMS表现出不同的影响.
结论:
- 了解抗抑郁药的机制对于治疗抑郁症患者的PLMS至关重要.
- 需要进一步的研究来优化伴随性抑郁症和PLMS的治疗策略.
关键词:
抗抑郁药是一种抗抑郁药.神经递质神经递质在 PLMD PLMD 中.在 PLMS PLMS 中.这是SNRI的SNRI.这是一个SSRI.睡眠障碍 睡眠障碍 睡眠障碍 睡眠障碍与睡眠相关的运动.三环抗抑郁剂三环抗抑郁剂更多相关视频
06:23A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
5.3K
05:59Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
Published on: October 20, 2023
2.3K
相关概念视频
REM Sleep Behavior Disorder
161
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
161
Sedatives and Hypnotics Drugs: Miscellaneous Agents
157
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
157
Restless Leg Syndrome and Night Terrors
154
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
154
Sleepwalking and Sleep Talking
124
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
124
Management of Insomnia
235
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
235
Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K
