心脏-产科研究的结果报告:系统性审查
Chelsea Hall1, Anna Shishkina2, Robin Thurman3
1Faculty of Medicine, University of Toronto, Toronto, Canada; Department of Obstetrics & Gynaecology, University of Toronto, Toronto, Canada; Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
American heart journal
|September 26, 2024
概括
心脏-产科研究报告结果不一致,阻碍了比较. 怀孕期间心脏病的新核心成果集 (COSCarP) 将为更好的研究标准化报告.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 周围生理学 周围生理学
- 系统审查是系统的审查.
- 进行元分析分析.
背景情况:
- 心脏-产科研究在结果定义和报告中表现出显著的变化.
- 这种变化的程度尚未被系统地记录下来.
- 标准化报告对于比较研究和进行心脏-产科的元分析至关重要.
研究的目的:
- 系统地审查和强调心脏-产科研究中结果报告的差异.
- 为制定怀孕期间心脏病核心结果集 (COSCarP) 提供信息.
主要方法:
- 在Medline,Embase,Web of Science和Cochrane中央数据库 (1980-2018) 中进行系统搜索.
- 包括所有关于怀孕和心脏病的英语出版物.
- 重复查和数据提取研究细节,患者群体和报告结果的数据.
主要成果:
- 对422项心脏和产科研究的分析显示,结果报告中存在广泛的不一致性.
- 报告的孕产妇死亡率因原因 (全因,心脏病,产科) 和时间框架而异,其中41%缺乏具体说明.
- 还观察到心力衰竭,围产损失,胎儿生长,出血,心律失常,早产,血栓栓塞和高血压疾病的不一致报告.
结论:
- 这一综述强调了对心脏-产科标准化结果报告的极大需要.
- 不一致的报告阻碍了研究比较和元分析.
- 发展中的COSCarP旨在为未来的研究提供一个最小的,基于共识的结果集.
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