经过手术治疗的慢性大鼻炎:单独或与真菌球结合的牙病原病因是否重要?
Edouard Di Donna1, Alexandre Perez1, Julien Wen Hsieh2
1Service of Oral and Maxillofacial Surgery, Department of Surgery, Faculty of Medicine, University of Geneva & University Hospitals of Geneva, Geneva, Switzerland.
Journal of stomatology, oral and maxillofacial surgery
|September 26, 2024
概括
没有真菌球的牙性大鼻炎显示出更好的治疗成功. 带有真菌球的牙性大鼻炎是一种具有挑战性的疾病,结果较差,需要密切监测患者.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 犀牛鼻学 犀牛鼻学
- 医学研究 医学研究
背景情况:
- 慢性鼻炎 (CMS) 带来了诊断和治疗方面的挑战.
- 区分臭源与非臭源的原因对于有效的管理至关重要.
- 球在牙性鼻炎的结果中的作用需要进一步阐明.
研究的目的:
- 为了比较临床特征和治疗结果的牙性大鼻炎 (OMS) 和没有真菌球 (FB) 与非牙性大鼻炎 (非OMS).
- 为了确定影响不同类型的鼻炎治疗成功的因素.
主要方法:
- 对200名接受CMS手术的患者进行了回顾性队列研究 (2013-2021).
- 将患者分为非OMS,没有真菌球的OMS (OMSw/oFB) 和有真菌球的OMS (OMSwFB).
- 使用后勤回归分析了临床表现,术后并发症和治疗结果.
主要成果:
- 多变量分析显示,OMSw/oFB的成功治疗率明显更高 (OR = 8.19,p < 0.01).
- OMSwFB与不太有利的结果相关 (OR = 0.27,p = 0.03).
- 高龄与两个OMS组的不良结果相关 (OR:0.98,p = 0.03).
结论:
- OMSwFB代表了OMS的反抗性形式,与持续的症状和较差的治疗结果有关.
- 患有OMSwFB的患者应接受关于疾病具有挑战性的性质的咨询.
- 建议对被诊断患有OMSwFB.B.的患者进行密切监测.
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