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Updated: Jun 12, 2025

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
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Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

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通过聚合物对手和突变调节的液体-液体相分离后的细胞蛋白形态转移

Yangyi Liu1,2, Marcus D Tuttle1, Mikhail A Kostylev2

  • 1Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06511, United States.

Journal of the American Chemical Society
|September 26, 2024
PubMed
概括

蛋白 (PrPC) 的液态相分离 (LLPS) 需要一个成熟过程. 这种由突变和PSCMA加速的形状变化可能会导致神经退化.

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Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster10:26

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Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

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