在狗中对Babesia microti的分子流行,流行病学和遗传学分析,并说明其对宿主血液学概况的影响
Muhammad Ali1, Madiha Rasool2, Ahmad Ali1
1Department of Zoology, The Islamia University Bahawalpur, 60800, Pakistan.
Veterinary parasitology, regional studies and reports
|September 26, 2024
概括
巴比西亚微型菌被检测到巴基斯坦4%的狗. 受感染的狗表现出红细胞分布的改变,强调了对这种动物性寄生虫的控制策略的必要性.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 分子流行病学分子流行病学
- 一个健康,一个健康.
背景情况:
- 贝贝西亚微型是一种内红细胞原生体寄生虫,具有广泛的宿主范围,包括人类和动物.
- 了解它在像狗这样的家禽中的患病率对于公众健康至关重要,因为它具有动物传染的潜力.
研究的目的:
- 确定巴基斯坦旁遮普省和开伯尔帕赫图努克瓦省犬群中Babesia microti的流行率.
- 分析B. microti分离物的血液学概况,风险因素和遗传学多样性.
主要方法:
- 来自五个地区的654只看似健康的狗使用PCR进行了查.
- 通过对18S rRNA基因的桑格测序证实了阳性样本.
- 评估了血液学参数和潜在的风险因素.
主要成果:
- 在4% (29/654) 的狗中检测到Babesia microti.
- 遗传学分析显示与全球分离物有相似之处.
- 受感染的狗表现出红细胞分布宽度变化系数 (RDW-CV) 的升高.
- 在患病率和采样地点,犬种,性别或外寄生虫存在之间没有发现显著的关联.
结论:
- 这项研究提供了巴基斯坦犬中Babesia microti的最新流行数据.
- 研究结果强调了通过虫传染给人类的可能性,强调了需要综合控制策略的必要性.
- 感染狗的改变RDW-CV可以作为诊断指标.
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