精神疾病和COVID-19疫苗接种:对基于观察和登记的数据进行跨国调查
Mary M Barker1, Kadri Kõiv2, Ingibjörg Magnúsdóttir3
1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. mary.barker@ki.se.
Nature communications
|September 26, 2024
概括
在患有精神疾病的人群中,COVID-19疫苗的接种率通常很高. 然而,在没有药物治疗的精神疾病患者中观察到疫苗接种率略有下降,这需要进一步调查.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 患有精神疾病的人面临严重COVID-19结果的风险较高.
- 此前对这一人口群体的COVID-19疫苗接种率的研究已经产生了不一致的结果.
- 了解疫苗接种模式对于减轻脆弱人群中COVID-19的严重程度至关重要.
研究的目的:
- 调查精神疾病和COVID-19疫苗接种之间的关联.
- 分析不同人群和方法的疫苗接种数据.
- 确定精神疾病患者在接种或接受疫苗方面的潜在差异.
主要方法:
- 七个跨国COVIDMENT联盟队列研究的元分析 (N=325,298).
- 分析瑞典国家卫生登记册数据 (N=8,080,234).
- 通过自我报告,临床诊断和处方数据定义的精神疾病.
主要成果:
- 从COVIDMENT研究中汇集的元分析通常显示,精神疾病和接种疫苗之间没有显著的联系.
- 瑞典注册数据显示,精神疾病患者的第一剂和第二剂COVID-19疫苗接种量略有减少.
- 这种减少在未服用药物的精神疾病患者中比服用精神病药物的患者更为明显.
结论:
- 总体而言,在患有和没有精神疾病的个人中,COVID-19疫苗的接种率很高.
- 在未服用药物的精神疾病患者小组中,较低的疫苗接种率需要进一步关注和有针对性的策略.
- 确保所有人,包括患有精神疾病的人均获得公平的疫苗接种仍然是公共卫生优先事项.
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