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Updated: Jun 12, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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Published on: November 2, 2018

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A20的NF-κB调控表达控制了激活的T细胞中RIPK1诱导的细胞死亡的IKK依赖抑制

Scott Layzell1, Alessandro Barbarulo1, Geert van Loo2

  • 1Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, The Pears Building, Hampstead, London, UK.

Cell death and differentiation
|September 26, 2024
PubMed
概括

IKK信号保护激活的T细胞免受RIPK1依赖的死亡. 这涉及直接的RIPK1酸化和NF-κB介导的A20诱导,对于T细胞存活至关重要.

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