对比热量限制方案,以有效管理成人的体重:一个系统的审查和网络元分析
Jinming Huang1, Yi Li1, Maohua Chen2
1Department of Rehabilitation Medicine, Key Laboratory of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China.
The international journal of behavioral nutrition and physical activity
|September 26, 2024
概括
替代性禁食 (ADF) 导致了四种流行的饮食中最显著的体重减轻. 虽然所有饮食都显示出初步的成功,但长期干预 (7-12个月) 会产生更好的体重控制结果.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 肥胖问题研究研究
背景情况:
- 热量限制 (CR) 方案有效降低与肥胖相关的健康风险.
- 成年人体重管理的最佳CR疗法尚不清楚.
研究的目的:
- 系统地比较四种CR方案的减肥效果:交替禁食 (ADF),短期禁食 (STF),时间限制饮食 (TRE) 和持续能量限制 (CER).
- 评估二次结果,包括BMI,身体组成,代谢标志物和不良事件.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane CENTRAL的系统文献搜索到2024年1月.
- 包括47个随机对照试验 (RCT) 与3363名成年参与者.
- 贝叶斯网络元分析根据减肥和其他结果对治疗方案进行排名,使用网络元分析工具对研究质量进行评估.
主要成果:
- 替代性禁食 (ADF) 显示最显著的体重减轻 (MD: -3.42 kg),其次是时间限制饮食 (TRE) (MD: -2.25 kg).
- 短期禁食 (STF) 导致瘦肉量下降 (MD:-1.26公斤),而TRE改善了禁食葡萄糖 (MD:-2.98).
- 大多数治疗方案,特别是CER,在4-6个月后恢复体重,但更长的干预 (7-12个月) 显示持续减肥,TRE可能导致.
结论:
- 所有四种CR疗法都对减肥有效,ADF显示最大的影响.
- 适度的初始减肥在各种方案中是常见的,但持续的减肥在更长的干预期 (7-12个月) 时更有可能发生.
- 对于长期的体重控制和代谢改善,TRE可能特别有效.
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