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在急性缺血性中风患者的pRESET血栓切除器件结局:系统性审查和元分析

Abdelrahman M Hamouda¹, Mark Cwajna², Hassan Kobeissi¹

¹Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

|September 27, 2024

概括

在急性缺血性中风患者中,pRESET支架检索器系统有效地清除大血管封闭. 这一元分析证实了其与现有的机械血栓切除器件相比较的安全性和有效性.

科学领域:

神经学神经学
干预性神经辐射学
脑卒中医学脑卒中医学

背景情况:

由于大血管封闭 (LVO) 的急性缺血性中风需要及时的机械血栓切除术.
有各种可用于LVO治疗的支架回收器系统.
对于pRESET支架回收器系统的有效性和安全性,需要进行详细的评估.

研究的目的:

在急性缺血性中风中对机械血栓切除术 pRESET 支架检索器系统的疗效和安全进行系统性审查和元分析.
为了比较pRESET系统的性能与已建立的血栓切除装置.

主要方法:

进行了全面的系统审查和元分析.
研究在主要数据库 (PubMed,Scopus,Web of Science,Embase) 中进行了系统的搜索,直到2024年3月.
在选择相关研究时,采用了包含/排除标准.

主要成果:

分析了8项涉及1140名患者的研究.
pRESET系统实现了53.4%的第一通效果和90.41%的脑梗塞中血栓溶解 (TICI) 2b-3再输率.
九十天的结果包括42.2%的修改的兰金尺度 (mRS) 分数为0-2和15.1%的死亡率,其中28.6%经历了干预后出血.

结论:

在 pRESET 支架回收器系统证明了显著的有效性,在实现急性缺血性中风的再注射.
它的安全性和有效性概况与目前使用的其他机械血栓切除器械相提并论.
这一元分析支持pRESET系统在临床实践中用于LVO管理的使用.

关键词:

缺血性中风是因为缺血性中风.这是内血管内血管的内血管.普雷塞特 (Preset) 的意思支架回收犬支架回收犬进行血栓切除术 (thrombectomy).

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