儿童肠杆菌血流感染的趋势
Anna A M Gibbs1,2, Kevin B Laupland3,4, Felicity Edwards3
1UQ Centre for Clinical Research, University of Queensland, Brisbane, Queensland, Australia.
Pediatrics
|September 27, 2024
概括
昆士兰州儿童中肠杆菌血流感染 (E-BSI) 的发生率从2000年至2019年几乎翻了一番,主要是由于大肠杆菌和沙门氏菌的增加. 这一增长凸显了儿童感染中抗菌素耐药性的担忧日益增加.
科学领域:
- 儿童传染病 儿童传染病
- 微生物学 微生物学
- 流行病学 流行病学
背景情况:
- 肠杆菌血流感染 (E-BSI) 代表了儿童的重大健康负担.
- 抗微生物耐药性是与E-BSI相关的日益关注的问题.
研究的目的:
- 评估澳大利亚昆士兰州儿童以人口为基础的E-BSI发病率的时间变化.
- 分析特定病原体和抗菌素耐药性的趋势.
主要方法:
- 一项队列研究分析了2000年至2019年昆士兰州儿童的E-BSI病例.
- 数据与住院病例和重要统计数据联系在一起,以确定发病率.
- 二级结局包括扩展谱β-乳糖酶 (ESBL) 的流行,停留时间和死亡率.
主要成果:
- 年龄和性别标准化的E-BSI发病率每年增加3.9%,在20年内几乎翻了一番.
- 大肠杆菌和沙门氏菌的血液感染每年显著增加,分别为4.7%和13.7%.
- 扩展光谱β-乳糖酶产生大肠杆菌的比例也增加了.
结论:
- 昆士兰州的儿科E-BSI发病率在过去20年里显著增加.
- 沙门氏菌和大肠杆菌的增长率,以及抗药性增加,需要采取行动.
- 建议将儿童纳入抗微生物药物的临床试验.
更多相关视频
06:20Detection of Enterohemorrhagic Escherichia Coli Colonization in Murine Host by Non-invasive In Vivo Bioluminescence System
Published on: April 9, 2018
9.4K
08:30One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures
Published on: July 9, 2012
25.4K
相关概念视频
Urinary Tract Infection II: Pathophysiology
2
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
2
Urine Studies II: Urine Culture and Sensitivity Test
3
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
3
Acute Pyelonephritis II: Diagnostic Studies and Management
2
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
2
