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Updated: Jun 12, 2025

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在晚期甲状腺癌中,Wnt/B-catenin激活和TP53突变与明显的免疫特征有关

Sonia Moretti1, Martina Mandarano2, Elisa Menicali1

  • 1Section of Internal Medicine and Endocrine and Metabolic Sciences, Department of Medicine and Surgery, University of Perugia, Perugia 06132, Italy.

The Journal of clinical endocrinology and metabolism
|September 27, 2024
PubMed
概括

具有TP53突变的无塑性甲状腺癌 (ATC) 显示出活跃的免疫反应,而具有Wnt/β-catenin通路激活的差异化甲状腺癌 (PDTC) 在免疫学上是惰性的. 这些发现凸显了甲状腺癌中独特的免疫特征.

关键词:
这就是b-catenin.免疫检查点抑制剂 免疫检查点抑制剂免疫类型 免疫类型在 p53 里,p53 是一个 p53 的代码.甲状腺癌是甲状腺癌.

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