血压与老年痴呆症之间的关联:来自中国的横截面研究
Tingting Yi1,2,3, Zhou Su3, Jiyang Wang1,2,4
1Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.
Frontiers in aging neuroscience
|September 27, 2024
概括
腹压血压 (DBP) 显示了与老年人痴呆风险的U形联系,85mmHg是最佳的. 血压指数 (BPI) 也与痴呆风险相关,突出了它们在预防策略中的重要性.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 心血管医学 心血管医学
背景情况:
- 老年人血压 (BP) 和痴呆症之间的关系尚未完全理解.
- 现有的研究已经产生了关于BP指标和痴呆症风险的不一致的发现.
研究的目的:
- 调查65岁及以上个体中各种血压指标与痴呆症之间的关联.
- 为了确定与痴呆风险增加相关的特定血压值.
主要方法:
- 2019年对3599名65岁以上的参与者进行了一项横截面调查.
- 进行了血压测量和神经心理评估.
- 通用增材和后勤回归模型分析了BP指标 (SBP,DBP,MAP,PP,BPI) 和痴呆症之间的关联.
主要成果:
- 在透析压 (DBP) 和痴呆症之间观察到U形关系,特别是在男性和70岁以上的人群中.
- 最低的痴呆风险与85mmHg的DBP相关.
- 血压升高 (<80 mmHg或≥100 mmHg) 和较高的血压指数 (BPI) 与痴呆症风险增加有显著关联.
结论:
- 腹压血压 (DBP) 在老年人中表现出与痴呆症的U形关联.
- 血压指数 (BPI) 显示了与痴呆风险的线性关系.
- DBP和BPI是BP管理策略的关键指标,旨在预防或延迟老年人痴呆的发病.
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