尼日利亚甲状腺癌的模式:系统审查和元分析
Taoreed Adegoke Azeez1, Oluwadamilare Iyapo2, Sharif Adeniyi Folorunso3
1Department of Medicine, Reddington Multi-Specialist Hospital, Lagos, Nigeria.
Indian journal of surgical oncology
|September 27, 2024
概括
甲状腺癌在尼日利亚女性中更为常见,特别是在中年. 乳头甲状腺癌现在是最常见的类型,从以前的毛囊主导转变.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 甲状腺癌是最常见的内分泌恶性瘤.
- 组织病理学变异需要量身定制的治疗方法,并影响患者的治疗结果.
- 了解尼日利亚甲状腺癌的流行病学模式对于公共卫生战略至关重要.
研究的目的:
- 阐明尼日利亚甲状腺癌的流行病学模式和组织病理学分布.
- 确定尼日利亚人口中的人口趋势和常见的癌症类型.
- 分析近几十年来甲状腺癌亚型的变化.
主要方法:
- 在多个数据库 (如PubMed,SCOPUS,African Journal Online) 和预印服务器上进行了系统的文献搜索.
- 研究质量使用纽卡斯尔-太华尺度进行评估.
- 用Meta XL进行了元分析,采用随机效应模型,并评估I2和Cochran的Q测试的异质性. 出版偏差是使用LFK指数和Doi图进行评估的.
主要成果:
- 该分析包括26项研究,共1224名患者.
- 甲状腺癌主要发生在40岁和50岁的人身上.
- 这种情况在女性中比男性更常见3.5倍.
- 综合比例显示,乳头类甲状腺癌的比例为46%,毛囊类甲状腺癌的比例为39%,髓类甲状腺癌的比例为7%,形甲状腺癌的比例为5%.
结论:
- 乳头甲状腺癌已经成为尼日利亚最常见的类型,标志着从以前的毛囊占主导地位的转变.
- 甲状腺癌的发病率在女性中较高,通常在中年人群中被诊断出来.
- 这些发现强调了尼日利亚针对甲状腺癌的查和管理策略的需要.
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