ENFORCER,为心脏骤停的幸存者提供基于互联网的干预:一种随机,并行组,多中心临床试验的研究方案
Lorenzo Gamberini1, Paola Rucci2, Camilla Dolcini3
1Department of Intensive Care and Prehospital Emergency, Emergency Department, Maggiore Hospital, Bologna, Italy.
Resuscitation plus
|September 27, 2024
概括
该ENFORCER试验调查了基于互联网的生活方式干预,用于医院外心脏骤停 (OHCA) 的幸存者. 该计划旨在改善认知和情绪健康,提高幸存者退院后的生活质量.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 医院外心脏骤停 (OHCA) 在欧洲构成重大健康风险,导致死亡率和幸存者的长期认知和情绪缺陷.
- 目前对OHCA幸存者的退院后护理不一致,往往无法解决残疾的认知和情绪症状.
- 幸存者由于认知障碍,焦虑和抑郁症而减少了生活质量.
研究的目的:
- 评估基于互联网的全面生活方式干预对OHCA幸存者的有效性.
- 通过解决认知和情绪缺陷,提高OHCA幸存者的健康和生活质量.
- 为OHCA幸存者建立一个标准化,可访问和具有成本效益的退院后护理模式.
主要方法:
- 一个多中心,并行组随机对照试验 (ENFORCER) 涉及18-80岁的OHCA幸存者.
- 认知障碍或焦虑/抑郁症的参与者被随机分配1:1到干预或标准护理组.
- 干预组通过一个安全的网络应用程序接受了一年的认知,情感和身体康复计划.
主要成果:
- 主要结局是1年内没有认知或情绪症状的患者比例.
- 二次结果包括认知/情绪症状的变化,生活质量,睡眠和性功能.
- 护理人员的负担和幸福感也被评估为次要结果.
结论:
- 该试验解决了OHCA后幸存者护理的关键差距,重点关注认知和情绪恢复.
- 基于互联网的干预提供了一个可扩展的,具有成本效益的解决方案,以改善OHCA幸存者的长期结果.
- 研究结果可能为OHCA后的护理制定新的标准,改善幸存者的康复和生活质量.
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