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肝氧在患有呼吸系统损害的儿童中使用的结果:一个10年的单一机构经验
Ashley Young1, Eli Stein2, Matthew Rowland3,4
1Department of Otolaryngology-Head and Neck Surgery Feinberg School of Medicine, Northwestern University Chicago Illinois USA.
Laryngoscope investigative otolaryngology
|September 27, 2024
概括
在患有呼吸系统损害的儿童中,Heliox治疗可能是暂时的解决方案. 长时间使用超过47小时,特别是神经肌肉或内疾病,增加了对外科呼吸道干预的需求.
科学领域:
- 儿科肺病学 儿科肺病学
- 关键护理医学 关键护理医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 氧混合物Heliox可改善气流并降低儿科患者的呼吸道阻力.
- 了解治疗heliox的儿童手术干预的长期结果和预测因素至关重要.
研究的目的:
- 评估在患有呼吸道损害的儿童中使用赫里奥克斯治疗的结果.
- 确定与需要呼吸道外科手术干预相关的因素.
主要方法:
- 在2012年至2022年期间,对119名接受了heliox治疗的儿童进行了回顾性队列研究.
- 分析患者人口统计学,并发症,hliox使用时间,以及需要呼吸道或呼吸道重建的需要.
主要成果:
- 大多数患者 (84%) 患有显著的并发症.
- 累计使用heliox超过47小时与需要气管切除术或呼吸道重建的6.2倍风险增加有关 (p<0.0001).
- 神经肌肉疾病,内神经病理学和长期使用赫里奥克斯与确定的呼吸道干预有关.
结论:
- 赫里奥克斯可以作为儿童上呼吸道阻塞的临时措施.
- 长期使用赫里奥克斯的有效性和必要性 (>47小时),特别是在患有神经肌肉疾病或内神经病理的儿童中,需要重新考虑.
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