绘制和可视化全球关于卵巢癌中二维基提纳酶的研究进展:一个图书统计分析
Fang Qiu1, Yuntong Li2, Lile Zhou1
1Department of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, Guangdong, China.
Frontiers in pharmacology
|September 27, 2024
概括
这项文献计量研究绘制了卵巢癌中二基化酶 (DUBs) 的研究. 它强调了关键的机构,作者和DUBs的新兴趋势.
科学领域:
- 在瘤学瘤学.
- 生物化学 生物化学
- 分子生物学分子生物学
背景情况:
- 卵巢癌是一种具有不良预后和有限治疗选择的侵袭性恶性瘤.
- 脱化酶 (DUBs) 是蛋白质泛化的关键调节者,影响癌症的发展.
- 了解DUBs的作用对于推进卵巢癌治疗至关重要.
研究的目的:
- 绘制和可视化研究趋势在卵巢癌中使用图书识别对二化酶 (DUBs) 的研究.
- 总结DUBs在卵巢癌中的表达模式和生物功能.
- 确定该领域领先的研究机构,作者和期刊.
主要方法:
- 从科学网络核心收藏中对243篇文章进行了图书统计分析.
- 使用VOSviewer,CiteSpace和R软件进行可视化.
- 关键词爆发分析以确定研究热点.
主要成果:
- 在DUB和卵巢癌研究中,出版趋势越来越大.
- 中国,美国和英国是领先的研究国家;约翰霍普金斯大学,Genentech和罗氏是关键机构.
- 顶级作者包括大卫·科曼德,齐华·和理查德·罗登.
- 关键的研究领域包括DUB表达,激活,降解和无处不在.
- DUBs在卵巢癌的发病,生长,化学抵抗和转移中发挥着重要作用.
结论:
- 这项研究提供了对三十年来卵巢癌研究中的DUBs的全面概述.
- 它确定了有影响力的作品,关键参与者和新兴研究方向.
- 对DUB的作用的洞察力为卵巢癌提供了潜在的治疗点.
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