晚期早产婴儿呼吸道发病率的种族差异:一项回顾性队列研究
Theodore Dassios1,2, Allan Jenkinson1, Ravindra Bhat3
1King's College London, London, UK.
与白人婴儿相比,黑人晚期早产婴儿的呼吸系统发病率较低,需要更少的通风和更短的住院时间. 这项研究强调了晚期早产新生儿呼吸结果的种族差异.
科学领域:
- 新生儿科学 新生儿科学
- 儿科呼吸系统医学 儿科呼吸系统医学
- 健康差异 在健康上的差异
背景情况:
- 晚期早产婴儿 (怀孕34至<37周) 患呼吸道疾病的风险增加.
- 这种人群中种族对呼吸系统结果的影响尚未得到充分证实.
研究的目的:
- 为了调查黑人和白人晚期早产婴儿之间新生儿呼吸系统发病率的种族差异.
- 为了根据种族来比较呼吸辅助和医疗保健资源利用率的发生率.
主要方法:
- 在一个单一的英国中心进行的回顾性队列研究.
- 包括34周到37周妊娠年龄之间出生的婴儿.
- 主要结局指标是侵入性通风的发生率.
主要成果:
- 与白人婴儿 (n=673) 相比,黑人婴儿 (n=354) 的侵入性通风率 (19%对27%) 和非侵入性通风率 (22%对34%) 显著降低.
- 黑人婴儿的住院时间更短,相关费用更低.
- 对所有主要和次要结果 (通风P < .001 ,持续时间P = .011,成本P < .001) 观察到统计学意义.
结论:
- 黑人晚期早产婴儿需要的呼吸支持,包括侵入性和非侵入性通风,比他们的白人同行少.
- 在晚期早产新生儿的呼吸系统发病率和医疗保健利用率方面存在种族差异.
- 需要进一步的研究,以了解导致这些观察到的差异的潜在因素.
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