Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

ERK autoinhibition mechanism informs a drug combination strategy.

Protein science : a publication of the Protein Society·2026
Same author

Energy landscapes in molecular biology: History, principles, and perspectives.

Quarterly reviews of biophysics·2026
Same author

Introduction to "Endocytosis and cellular delivery".

RSC chemical biology·2026
Same author

Interactions of POPC Liposomes with Graphene Investigated by Quartz Crystal Microbalance and All-Atom Molecular Dynamics Simulations.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Leveraging conformational ensembles in allosteric drug discovery.

Trends in pharmacological sciences·2026
Same author

Allosteric drugs in biomolecular condensates: ways forward.

Drug discovery today·2026

相关实验视频

Updated: Jun 16, 2026

Author Spotlight: Affinity Purification of a Fibrinolytic Enzyme from Sipunculus nudus
06:45

Author Spotlight: Affinity Purification of a Fibrinolytic Enzyme from Sipunculus nudus

Published on: June 2, 2023

2.1K

一种可光切换的酸纤维化酶.

Mousumi Samanta1,2, Noy Saad1, Dinghao Wu3

  • 1Chemistry Department, Ben-Gurion University of the Negev, Campus st. 1, Beer Sheva, 8410501, Israel.

Angewandte Chemie (International ed. in English)
|September 27, 2024
PubMed
概括

研究人员开发了一种对光敏感的催化剂,可以使用紫外线和可见光开启和关闭. 这种可光切换的催化剂模仿了酶活性,为纳米技术应用提供了精确的控制.

关键词:
动态自组装自组装系统灯光触发触发的灯光,可以触发.类催化剂的催化作用立体选择性催化剂.系统化学 系统化学

更多相关视频

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation
19:23

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation

Published on: January 16, 2019

9.2K
A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on: January 9, 2019

33.1K

相关实验视频

Last Updated: Jun 16, 2026

Author Spotlight: Affinity Purification of a Fibrinolytic Enzyme from Sipunculus nudus
06:45

Author Spotlight: Affinity Purification of a Fibrinolytic Enzyme from Sipunculus nudus

Published on: June 2, 2023

2.1K
Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation
19:23

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation

Published on: January 16, 2019

9.2K
A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on: January 9, 2019

33.1K

科学领域:

  • 超分子化学 超分子化学
  • 催化剂是一种催化剂.
  • 类纳米技术 类纳米技术

背景情况:

  • 使用类催化剂模仿酶催化,可以增强反应,但缺乏外部调节.
  • 光照射为分子功能提供了精确的时间和空间控制.
  • 可光切换的分子是各种反应介质的需求调节的理想选择.

研究的目的:

  • 选择和表征一个可光切换的两类催化剂.
  • 调查组合中催化活性的光诱导调节.
  • 为纳米技术探索可逆自组合的潜力.

主要方法:

  • 选择含有亚博和伊斯蒂丁残留物的异构.
  • 研究紫外线和可见光对纤维分解和重组的影响.
  • 酶选择性水解试验用于量化催化活性.

主要成果:

  • 选择了一种可光切换的催化剂,在纤维状形式表现出高效的酶选择性水解.
  • 紫外线光诱导的跨-至-晶亚博同质化分解了纤维,显著降低了催化活性.
  • 在可见光照射时,催化活性被可逆地恢复,使多个开/关周期成为可能.

结论:

  • 可光切换的类催化剂提供精确的,光介导的控制催化功能.
  • 纤维的可逆自组装和拆卸可以由光触发.
  • 这项研究提供了关于早期化学进化的见解,并推进了类纳米技术.