T2映射的可行性和可重复性与在固体脏群体中扩散权重成像相比
Shichao Li1, Mengmeng Gao1, Kangwen He1
1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Bioengineering (Basel, Switzerland)
|September 27, 2024
概括
运动强大的辐射T2映射精确地区分质量,并预测清细胞细胞癌 (ccRCC) 的等级和阶段. 这种定量MRI技术对多参数脏成像具有前景.
科学领域:
- 放射学和医学成像学 医学成像学
- 在瘤学瘤学.
- 脏病理学 脏病理学
背景情况:
- 准确的质的特征,包括亚型,WHO/ISUP等级和清细胞细胞癌 (ccRCC) 的病理T (pT) 阶段,对于患者的管理至关重要.
- 目前的成像技术在区分特定的质子类型和分类ccRCC时可能存在局限性.
研究的目的:
- 评估可行性和可重复性运动强的辐射T2映射的可行性和可重复性,以区分脂质贫乏血管脂质瘤 (MFAML) 和RCC.
- 调查辐射T2映射在描述ccRCC的WHO/ISUP等级和pT阶段的有用性.
- 为了比较T2映射与扩散权重成像 (DWI) 的性能,使用明显扩散系数 (ADC) 值.
主要方法:
- 92名患者接受了脏辐射T2映射和ZOOMit DWI.
- 分析了T2值和ADC值.
- 在ADC和T2值之间计算了相关系数.
主要成果:
- 清晰细胞细胞癌 (ccRCC) 与脂质贫血血管瘤 (MFAML) 相比显示显著更高的T2和ADC值 (p <0.05).
- 在ccRCC中,T2值与更高的WHO/ISUP等级和pT阶段相反相关 (p <0.05).
- T2映射显示,在评估WHO/ISUP等级 (0.936) 和ADC (0.817) (p = 0.027) 的曲线下面面积 (AUC) 较高.
- T2值与ADC有中度正相关 (r = 0.675,p < 0.001).T2值与ADC有中度正相关 (r = 0.675,p < 0.001).
结论:
- 定量运动坚固的辐射T2映射是一种可行的技术,用于表征固体质.
- 辐射T2映射在多参数成像中提供了附加值,用于预测ccRCC的WHO/ISUP等级和pT阶段.
- 这种技术可以提高诊断准确度,并有助于对瘤的临床决策.
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