直接口服抗凝剂和牙拔除后的出血管理-一个前性队列研究
Rossana Izzetti1, Chiara Cinquini1, Marco Nisi1
1Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University Hospital of Pisa, 56126 Pisa, Italy.
Dentistry journal
|September 27, 2024
概括
直接口服抗凝剂 (DOACs) 可能会增加牙拔除后的出血,特别是在更复杂的手术中. 虽然DOAC悬浮剂可以减少术前出血,但术后出血不受影响.
科学领域:
- 牙科 牙科是指牙科的专业.
- 药理学 药理学是指药理学的学科.
- 心脏病学 心脏病学
背景情况:
- 直接口服抗凝剂 (DOAC) 越来越多地用于血栓预防.
- 在DOAC患者的牙提取需要谨慎管理,以防止出血并发症.
研究的目的:
- 评估用DOACs治疗的患者在牙提取后发生的内,周围和术后出血的发生率.
- 为了确定与增加出血风险相关的因素.
- 评估DOAC疗法修改对出血结果的影响.
主要方法:
- 对49名接受牙科拔牙的患者进行前性研究.
- 在手术前,DOAC疗程要么维持,要么暂时暂停.
- 在手术期间,手术期间和手术后7天内,血流被仔细监测.
- 根据提取的牙数量,板升高和骨切除的情况,患者被分为小组.
主要成果:
- 超过三次拔牙,片升高和骨切除术显著与更高的出血率相关 (p < 0.05).
- 里瓦罗克萨班和阿皮克萨班使用者经历了更频繁的出血发作.
- DOAC 悬浮与手术前出血减少有关,但与术后出血无关.
结论:
- 虽然DOACs可以增加牙提取后的出血风险,但发作通常是轻微的和可控的.
- 在特定的牙科手术中,DOAC悬浮剂可能有利于管理术后出血.
- 需要进一步的研究来优化牙科手术的抗凝固管理策略.
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