含有异盐的新型牙膏配方在预防牙损伤方面的有效性:一项微生物研究
Bennett Tochukwu Amaechi1, Parveez Ahamed Abdul Azees1, Sahar Mohseni1
1Department of Comprehensive Dentistry, School of Dentistry, University of Texas Health San Antonio, San Antonio, TX 78712, USA.
Dentistry journal
|September 27, 2024
概括
与化 (CPC) 配合的异盐和化牙膏显著降低了非矿物化,与仅含化的牙膏相比,提供更好的牙预防. 这种组合有效地打击了牙损的发展.
科学领域:
- 牙科研究 牙科研究
- 牙损伤预防 牙损伤的预防
- 生物材料科学是生物材料的科学.
背景情况:
- 牙损仍然是一个重要的全球健康问题.
- 化物是预防空的一个关键因素.
- 正在探索像伊索马尔特和化 cetylpyridinium (CPC) 这样的新成分,以提高有效性.
研究的目的:
- 评估含有异,化物和CPC的牙膏的抗牙疗效.
- 为了比较不同的牙膏配方在防止牙面膜去矿物化的有效性.
主要方法:
- 人体质板被接受了为期7天的微生物虫模型.
- 牙膏配方包括异,化物和CPC或酸 (SLS) 的不同组合.
- 用横向微射线学测量表面微硬度 (ΔSMH) 和矿物损失 (∆Z) 的变化来量化非矿物化.
主要成果:
- 与基线相比,使用10%的异盐,1100ppm化物和0.05%CPC (ICT) 的牙膏没有显著的去矿化.
- 除了ICT之外,所有测试的牙膏组都表现出明显低于脱离离子蒸水 (DDW) 的去矿化.
- 与异盐/化物 (IT),仅化物 (FT) 和化物/SLS (FST) 组相比,ICT组显示出显著更大的去矿化抑制.
结论:
- 牙膏含有10%的异盐,1100ppm的化物和0.05%的CPC在预防牙的发展方面非常有效.
- 这种配方在抑制脱矿化方面表现出比仅含化物的牙膏更高的疗效.
- 异,化物和CPC的组合提供了一个有前途的策略,用于增强牙损伤的预防.
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