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Updated: Jun 12, 2025

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斯法洛可醇A衍生物:设计,合成和细胞毒性

Dídia Sousa1, Milene A G Fortunato2, Joana Silva1

  • 1MARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, ESTM, Politécnico de Leiria, 2520-614 Peniche, Portugal.

Marine drugs
|September 27, 2024
PubMed
概括

研究人员合成了Sphaerococcenol A的新型类似物,这是红藻中的一种化合物. 一些类似物显示出对癌细胞系有前途的细胞毒性活性,特别是化合物1和3,这表明有可能开发新的药物.

关键词:
藻类是一种藻类.这是一种抗癌药物.灭症 (apoptosis) 是一种死亡的过程.半合成 半合成 半合成 半合成 半合成海洋天然产品 海洋天然产品有活性氧物种的反应性氧物种.

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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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