在长时间坐着期间,坐着的中断模式在绝经后妇女的交叉试点试验中急剧改善了食后代谢
Jeffrey S Patterson1, Brinda K Rana2, Haiwei Gu1
1College of Health Solutions, Arizona State University, 850 N. 5th Street, Phoenix, AZ 85004, USA.
打破长时间的坐着与短暂的站立或散步休息可以改善老年妇女的心脏代谢健康标志物. 这些简单的中断可以减轻与久坐行为相关的风险.
科学领域:
- 老年学是一门学科.
- 代谢学 代谢学 代谢学
- 心血管健康 心血管健康
背景情况:
- 长时间坐着在老年人中很普遍,并且与慢性疾病有关.
- 身体不活动加剧了与衰老相关的健康风险.
- 久坐不动行为是心脏代谢疾病和癌症的独立风险因素.
研究的目的:
- 为了研究中断长时间坐着对绝经后妇女代谢概况的急性影响.
- 为了比较不同中断策略对心脏代谢标记物的影响.
主要方法:
- 对10名绝经后妇女随机对照交叉研究中的血样本的分析.
- 四个条件:控制的坐着,每20分钟站2分钟 (STS),每小时站10分钟 (Stand),每小时走2分钟 (Walk).
- 食和食后样本的有针对性的代谢分析.
主要成果:
- 短暂的中断 (STS,Stand) 阻止了对照组中发现的氨基酸代谢物的食后增加.
- 一种具有抗高血压和抗高血糖特性的诺瓦林衍生物在Stand和STS期间增加.
- 根据条件分组的代谢概况,由氨基酸,血管活性和糖代谢物驱动.
结论:
- 短暂的,低强度的休息可以诱导急性,有益的心脏代谢变化.
- 像STS和Stand这样的策略显示出改善风险高的绝经后妇女的代谢健康的前景.
- 暂停久坐可能是减轻心脏代谢风险的可行方法.
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