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Updated: Jun 12, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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铁素交互蛋白在NLRP3激活和骨关节炎发病过程中的作用:活体研究

Ruba Altahla1, Xu Tao1

  • 1Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Metabolites
|September 27, 2024
PubMed
概括

铁素相互作用蛋白 (TXNIP) 通过激活NLRP3炎症和热的通路来加剧骨关节炎 (OA). 在大鼠模型中,抑制TXNIP (敲除) 减缓了OA的进展,并保护了关节结构.

关键词:
在NLRP3中,NLRP3是NLRP3中的一个.在TXNIP中,您可以使用TXNIP.骨关节炎是一种关节炎.热灭菌的途径.

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