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Updated: Jun 12, 2025

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在多个结构类别中对和多基基物质 (PFAS) 进行体外肝清除评估

David M Crizer1, Julie R Rice1, Marci G Smeltz2

  • 1Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27711, USA.

Toxics
|September 27, 2024
PubMed
概括

这项研究扩展了使用人类肝细胞的和多基基物质 (PFAS) 的毒动力学 (TK) 数据. 这些发现使得更好的体外-体内抽取 (IVIVE) 模型能够评估这些新出现的污染物的人类健康风险.

关键词:
新方法方法 (NAMs)在PFAS中,有很多方法.生物转化过程中的生物转化.肝脏清除时间在体外体内外推算 (IVIVE)代谢 代谢 代谢 代谢毒性动力学 (TK) 是指毒性动力学

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