相关实验视频

Updated: Jun 11, 2025

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Published on: February 16, 2020

为创新,儿童友好的结核病儿科诊断方法铺平道路:乌克兰引入基于便的检测

Olena Diuzheva¹, Liudmyla Skoklyuk¹, Nina Zherebko¹

¹PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Tropical medicine and infectious disease

|September 27, 2024

概括

乌克兰的儿童结核病诊断正在通过便检测的整合而得到改善. 这种非侵入性方法有助于检测Mycobacterium tuberculosis (MTB) 和耐药菌株,特别是在无法产生的幼儿中.

科学领域:

儿科儿科儿科
传染性疾病传染性疾病
微生物学微生物学

背景情况:

诊断儿科结核病 (TB) 具有挑战性,因为它具有状结核性质,并且难以获得呼吸道样本.
乌克兰在有效诊断儿童结核病方面面临重大障碍.

研究的目的:

评估将便检测整合到常规儿科结核病服务中,以提高诊断效率.
评估便样本对于检测儿童中Mycobacterium结核病 (MTB) 和利芬素耐药性的有用性.

主要方法:

在乌克兰的12个区域结核病设施中进行了一项试点研究.
在2021年11月至2022年9月期间,从168名初步结核病诊断的儿童收集了便样本.
对便和其他可用的样本进行了细菌学分析,以确认MTB并检测耐药性.

主要成果:

在37名儿童中确诊了mycobacterium结核病 (MTB),其中18例是在便样本中检测到的.
便是18名儿童中7名儿童中MTB检测的唯一阳性样本.
在7名儿童中发现了利芬素耐药性,其中3例在便样本中检测到.

结论:

便检测是诊断儿科结核病,特别是幼儿结核病的有价值的非侵入性工具.
成功的试点实施导致乌克兰国家结核病计划在全国范围内采用便检测.
通过便分析及早检测结核病和耐药菌株,可以进行更有效,更安全的治疗,拯救生命.

关键词:

乌克兰乌克兰乌克兰乌克兰在Xpert MTB/RIF Ultra中使用.诊断算法诊断算法便样本/便样本/便样本儿科结核病儿童结核病结核病是一种肺结核病.

更多相关视频

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Published on: July 28, 2023

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Published on: July 22, 2012

相关概念视频

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Serum Laboratory Studies, Stool Test, Breath Test

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...