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Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...

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Updated: Jun 11, 2025

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice

Published on: February 9, 2014

[败血症的体外过程]

Alice Bernard, Michael Koeppen¹

¹Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Eberhard-Karls-Universität Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland. Michael.koeppen@med.uni-tuebingen.de.

Die Anaesthesiologie

|September 27, 2024

概括

治疗败血症的体外程序,如血过和细胞因子吸附,旨在去除炎症媒介,但缺乏已证明的生存益处. 需要进一步的研究来确定它们在治疗败血症患者中的有效性和安全性.

科学领域:

密集护理医学是密集护理的医学.
免疫学免疫学免疫学
腎臟病學 (nephrology) 是一種醫學專業.

背景情况:

败血症和败血性休克是危及生命的疾病,是由于免疫反应对感染的失调导致的.
这些情况在重症监护病房中普遍存在,并与高死亡率有关.

研究的目的:

提供各种用于治疗败血症和败血症休克的体外手术的概述.
评估有关这些治疗方法的有效性和安全性的现有证据.

主要方法:

对体外手术的审查,包括高容量血过 (HVHF),非常高容量血过 (VHVHF),高切断 (HCO) 过器,多素B血 perfusion 和细胞因子吸附过器.
包括联合血过和吸附 (CPFA) 和治疗性血交换 (TPE).

主要成果:

HVHF和VHVHF可以消除炎症媒介,但不能显著改善败血症患者的稳定性或生存率.
HCO过器去除细胞因子,但生存益处没有得到证实. 在特定群体中,多素B血 perfusion 显示出前景,而对细胞因子吸附过器的证据有限.
CPFA显示没有生存益处;TPE可能提供血管葡萄糖保护. 所有的手术都有风险,如血栓形成和必需蛋白质的损失.

结论:

关键词:

身体外的技术身体外的技术血液过血液过血液过血 perfusion 输血输血输血输血输血输血输血输血在等离子体交换的过程中,败血症的冲击是一个令人震惊的结果.

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Cecal Ligation Puncture Procedure

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目前用于败血症的体外手术的治疗益处尚不清楚.
进一步的大规模,随机化,多中心研究对于确定疗效和安全至关重要.
目前没有指导方针建议支持这些程序在败血症治疗中的常规使用.