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Updated: Jul 20, 2026

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound
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Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

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预测上腺染细胞瘤中的血管生成:来自对比度增强CT的修改参数的作用

Xing Xing1, Shao-Ping Cheng2, Jin-Bai Huang3

  • 1Department of Urology, The First Affiliated Hospital of Yangtze University Jingzhou, No. 8 of HangKong Road, ShaShi District, Jingzhou, 434000, Hubei, People's Republic of China.

Discover oncology
|September 27, 2024
PubMed
概括

双相对比增强CT参数,最大增强差异 (ΔH) 和最大增强速度 (V),可以预测色细胞瘤中的血管生成. 较高的 ΔH 和 V 值与微血管密度和 VEGF 表达率的增加相关.

关键词:
动脉阶段 动脉阶段双相增强CTCT是双相增强CT.微血管密度 微血管密度染细胞瘤 (Pheochromocytoma) 是一种细胞瘤.血管内皮生长因子 血管内皮生长因子静脉阶段 静脉阶段

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Mechanism of Angiogenesis01:10

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Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...