低压瓦萨尔瓦机动对大脑动脉硬度和脉冲波速度变化的影响
Eun-Seon Yang1, Ju-Yeon Jung2, Chang-Ki Kang1,2,3,4
1Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology (GAIHST), Gachon University, Incheon, Republic of Korea.
PloS one
|September 27, 2024
概括
低压瓦萨尔瓦机动 (VM) 在健康的年轻人中有效降低了脑血管硬和脉冲波速度 (PWV). 这种简单的技术提供了一种具有成本效益的方法来提高动脉弹性.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统功能 自主神经系统功能
- 大脑血管动力学
背景情况:
- 瓦萨尔瓦机动 (VM) 用于评估心血管和自主神经系统功能.
- 由VM引起的血液动力学变化会影响大脑血管功能,包括动脉弹性.
研究的目的:
- 为了研究低压VM对大脑动脉硬性的影响.
- 为了评估在低压VM后大脑血管动态的变化.
主要方法:
- 31名健康的年轻参与者进行了15秒的低压VM (30-35mmHg).
- 测量包括常见动脉 (CCA) 血管收缩和血管扩张直径 (VCD/VDD),血压 (SBP/DBP),平均动脉压 (MAP),脉冲压 (PP),脉冲波速度 (PWV),以及VM前后动脉硬.
- 统计分析比较了VM前后的参数.
主要成果:
- 低压VM显著增加了CCA VCD (2.15%) 和VDD (4.55%).
- 平均动脉压和透气血压显著增加 (分别为1.67%和1.10%).
- 在VM后观察到动脉硬度和PWV的显著降低 (p<0.001两者).
结论:
- 低压VM有效地减少了健康年轻人的脑血管硬和PWV.
- 这种机动代表了一种简单,具有成本效益的方法来提高脑血管弹性.
- 执行此干预不需要任何特定的环境条件.
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