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美国女性膀过活和药物治疗的趋势
Lauren A King1, Jessica E Pruszynski2, Clifford Y Wai3
1From the Department of Obstetrics and Gynecology and.
Urogynecology (Philadelphia, Pa.)
|September 27, 2024
概括
过度活性膀 (OAB) 的患病率正在增加,特别是在老年妇女中,但药物治疗仍然很低. 这突显了OAB症状管理中的重大差距,并表明需要增加查和干预.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 过度活跃的膀 (OAB) 影响着相当一部分人口,随着时间的推移,患病率会增加.
- 目前对症状性OAB的药物治疗率似乎很低,这表明潜在的治疗不足.
- 了解OAB患病率和治疗趋势对于公共卫生倡议至关重要.
研究的目的:
- 评估美国过度活动膀 (OAB) 患病率的趋势.
- 分析随着时间的推移对OAB药物的药理学处方实践的变化.
- 在不同的人口群体中识别OAB患病率和治疗的差异.
主要方法:
- 利用了2001-2019年国家健康和营养检查调查 (NHANES) 和国家门诊医疗调查 (NAMCS) 的数据.
- 雇员结合点回归分析OAB患病率和药物处方的趋势,调整关键的人口因素.
- 评估了总体趋势,并按种族,年龄,体重指数和保险状况分层.
主要成果:
- 整体而言,OAB患病率增加 (APC 1.24%),在2017-2018年达到31.2%,65岁以上女性的患病率最高 (54%).
- 药物治疗仍然很低 (3.5%的症状患者).
- 根据NAMCS数据,抗胆固醇药物处方显著下降 (APC -6.44%),而β3-上腺激素激剂处方保持稳定.
结论:
- 随着OAB的患病率上升,尤其是老年女性,再加上治疗率较低,表明治疗不足显著.
- 对于有症状的OAB患者,急需加强查和及时干预.
- 对OAB药物的处方模式正在发生变化,抗胆固醇药物的使用有显著下降.
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