眼运动水槽和垂体腺瘤:解剖学和临床研究
Simona Serioli1,2, Barbara Buffoli3, Marika Vezzoli4
11Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Division of Neurosurgery, Spedali Civili of Brescia, University of Brescia, Italy.
Journal of neurosurgery
|September 27, 2024
概括
由垂体神经内分泌瘤 (PitNETs) 引起的眼运动 (OMC) 参与是常见的,并影响患者的治疗结果. 内镜手术有效地治疗OMC参与,改善结果.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 神经解剖学是一个神经解剖学.
背景情况:
- 含有头骨神经III的眼运动 (OMC) 很少被研究,因为它很少涉及垂体神经内分泌瘤 (PitNET).
- 坑网可以压缩或入侵OMC,可能导致神经系统缺陷.
研究的目的:
- 在组织形态学上描述 OMC.
- 通过使用放射学,临床和手术数据,系统地分析PitNETs对OMC的参与.
- 评估OMC参与对患者结果和手术治疗的影响.
主要方法:
- 对10个半叶虫的基因组学分析.
- 针对PitNETs (2014-2021) 进行了内透手术的315名患者的回顾性审查.
- 对OMC参与 (压缩,入侵) 的分类以及与临床和放射学数据的相关性.
主要成果:
- OMC压缩发生在43.1%的患者中,入侵发生在9.3%的患者中.
- OMC参与与PitNET大小,Knosp等级,手术前的CN III,Ki-67和瘤复发有显著的相关性.
- 手术后的新CN III是2%,大多数病例是短暂的.
结论:
- 没有充分认识到PitNETs对OMC的重大参与.
- 透视性透视性手术是对OMC参与的有效治疗方法.
- 参与OMC显著影响患者的治疗结果,应该在治疗规划中考虑.
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