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Updated: Jun 24, 2026

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V-ATPase子单元在脂肪细胞分化中的不同功能及其在肥胖小鼠中的表达

Yuan Sun1, Xifeng Lu2, Maolin Wang3

  • 1College of Pharmacy, Shenzhen Technology University, Shenzhen, China.

Biochemical and biophysical research communications
|September 27, 2024
PubMed
概括

这项研究揭示了真空H+ ATPase (V-ATPase) 子单元在脂肪细胞发育 (脂肪生成) 中至关重要. 具体而言,v1a亚单元显著影响脂肪细胞分化,为肥胖机制提供了新的见解.

关键词:
增脂生殖是一种增脂的过程.胆固醇的新陈代谢肥胖问题 肥胖问题这是V-ATPase子单元.

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ATP Driven Pumps III: V-type Pumps01:30

ATP Driven Pumps III: V-type Pumps

V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...