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Updated: Jun 11, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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6-基甲基-7,8-二二蛋白酸酶的双基质抑制剂:对细胞透性进行研究

Genbin Shi1, Gary X Shaw2, Xinhua Ji1

  • 1Center for Structural Biology, National Cancer Institute, Frederick, MD 21702, USA.

Bioorganic & medicinal chemistry letters
|September 27, 2024
PubMed
概括

针对6-基甲基-7,8-二二二酸盐化酶 (HPPK) 的新型双基抑制剂显示出新抗生素的前景. HP-101证明了格拉姆阳性细菌的细胞透性,为未来的抗菌药物开发提供了一个框架.

关键词:
抗菌的 抗菌的 抗菌的双基质抑制剂的抑制剂叶酸是什么意思?叶酸是什么意思?这是HPPKK的.丁二甲是一种过渡状态模拟转换状态

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