Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Rapid Nanocellulose Wet Nanoimprint Lithography for Tunable Structural Color.

ACS nano·2025
Same author

Tunable Electrokinetic Motion of Charged Nanoparticles in an Aqueous Solution Using Interdigitated Microelectrodes.

Nanomaterials (Basel, Switzerland)·2025
Same author

Improving transport efficiency for large human cells for enabling accurate determination of cellular nanoparticle uptake via SC-ICP-TOF-MS.

Talanta·2025
Same author

Investigating the Nanoscale Dynamics of <i>Chlorella vulgaris</i> Flocculation with Pyridinium-Modified Cellulose Nanocrystals.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Quantitative DSC Assessment of the Polymorph-Specific Crystallinity of Poly(Lactic Acid) and the Impact of a Self-Assembling Nucleating Agent and PEG Plasticizer.

Polymers·2025
Same author

Laccase-Mediated Incorporation of Xylans and Lignin-Carbohydrate Complexes into High-Yield Eucalyptus Kraft Fibers.

ACS omega·2025

相关实验视频

Updated: Jun 16, 2026

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells
06:17

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

370

为3D心脏节拍提供光学活跃的纸质支架.

Fanglei Guo1, Stijn Jooken1, Amin Ahmad1

  • 1Laboratory for Soft Matter and Biophysics, Department of Physics and Astronomy, KU Leuven, 3001 Leuven, Belgium.

ACS applied materials & interfaces
|September 27, 2024
PubMed
概括

研究人员开发了一种新的基于纸张的脚手架,使用金纳米棒和量子点来光学控制心脏细胞. 这项技术可以通过近红外光对人工心脏组织进行精确的节奏和监测.

关键词:
3D心脏结构构造这是心肌细胞节奏.基于纸张的细胞支架架.通过等离子体调制进行等离子体调制.量子点纳米热度计的量子点.

更多相关视频

A Cardiac Microphysiological System for Studying Ca2+ Propagation via Non-genetic Optical Stimulation
08:29

A Cardiac Microphysiological System for Studying Ca2+ Propagation via Non-genetic Optical Stimulation

Published on: March 21, 2025

565
A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation
06:57

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation

Published on: August 5, 2018

8.9K

相关实验视频

Last Updated: Jun 16, 2026

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells
06:17

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

370
A Cardiac Microphysiological System for Studying Ca2+ Propagation via Non-genetic Optical Stimulation
08:29

A Cardiac Microphysiological System for Studying Ca2+ Propagation via Non-genetic Optical Stimulation

Published on: March 21, 2025

565
A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation
06:57

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation

Published on: August 5, 2018

8.9K

科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 纳米技术纳米技术

背景情况:

  • 目前用于调节心脏细胞活动的方法,如基于电极或光遗传学的方法,在空间分辨率和与3D构造的兼容性方面存在局限性.
  • 需要先进的体外平台用于心脏组织工程,药物查和疾病建模,提供精确的控制和监测能力.

研究的目的:

  • 设计和制造一个光可定位的,基于纸的纳米复合材料支架,用于光学节奏和读出体外心脏组织.
  • 研究使用金纳米棒 (GNR) 和量子点 (QD) 来精确调制和监测心肌细胞活动.
  • 评估这个平台作为心脏细胞操纵和组织工程现有方法的替代方案的潜力.

主要方法:

  • 使用GNR和QD功能化的纸纤维素微纤维制造纳米复合材料支架,嵌入原基质.
  • 利用调制的近红外 (NIR) 激光照明,通过GNRs诱导局部温度梯度,以调节心肌细胞活动.
  • 采用温度依赖的QD光发光 (PL) 来实时报告局部温度变化和监测细胞反应.

主要成果:

  • 纸质支架成功促进了HL-1心肌细胞的管状组织.
  • 使用GNRs进行NIR等离子体刺激,可实现心肌细胞活动的可逆调节.
  • QD光发光度提供了温度变化的准确读出,与细胞活动调制相关联.

结论:

  • 开发的基于纸张的纳米复合材料支架为光学节奏和心脏组织的读出提供了一个简单且可扩展的平台.
  • 这种基于NIR的方法提供了纳米空间分辨率,是基于电极或光遗传学方法的有希望的替代方案.
  • 该平台具有很大的潜力,可以推进体外药物查试验,并开发更准确的心脏病模型.