通过HALP得分预测复杂的急性椎炎:一项回顾性研究
Aziz Mutlu Barlas1, Saygın Altıner1, Abdurrahman Başpınar1
1Ankara Training and Research Hospital, Department of General Surgery, Ankara, Turkey.
Asian journal of surgery
|September 27, 2024
概括
结合血红蛋白,白蛋白,淋巴细胞和血小板水平的HALP得分,可以有效预测急性分歧炎的严重程度和预后. 这种廉价的标志物为更好的患者管理提供了对炎症和免疫营养状况的见解.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 急性膜炎在评估疾病严重程度和预后方面存在挑战.
- 现有的预后标志物可能无法完全捕捉炎症和免疫营养方面的因素.
- HALP评分 (血红蛋白,白蛋白,淋巴细胞,血小板) 提供了一个独特的综合评估.
研究的目的:
- 评价HALP得分在确定急性椎炎患者的疾病严重程度和预后方面的有用性.
- 将HALP得分的预后值与传统的炎症标志物进行比较.
- 为了评估HALP得分能够预测复杂与无复杂的分炎的能力.
主要方法:
- 一项回顾性研究包括190名被诊断患有急性膜炎的患者 (2017年1月 - 2023年6月).
- 患者根据Hinchey疾病严重程度分类进行了分层.
- 分析了炎症标志物的预后影响和HALP得分.
主要成果:
- 在复杂的分泌体炎病例中,观察到C-反应蛋白,白细胞计数,中性粒细胞计数,HALP得分和住院时间的中位数显著更高 (p < 0.001).
- 接收器操作特征 (ROC) 分析表明,HALP得分在预测分歧炎复杂性的有效性,曲线下的面积 (AUC) 为0.723 (p < 0.001).
- 一个HALP得分切线≤44.1显示了66.7%的灵敏度和75.0%的特异性来预测复杂的膜炎.
结论:
- HALP评分是评估急性椎炎严重程度的经济有效和安全的生物标志物.
- 它提供了有价值的预后信息,有助于临床决策.
- 哈尔普评分结合了炎症和免疫营养状况,用于全面评估患者.
更多相关视频
09:11Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
Published on: February 14, 2021
9.2K
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
31.7K
相关概念视频
01:29Appendicitis-II: Diagnostic Studies and Management
66
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
66
01:22Appendicitis-I: Introduction
91
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
91
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
94
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
94