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Updated: Jun 11, 2025

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催化无定向甲基化未激活的C-H键,适用于复杂分子

Jin-Fay Tan1, Yi Cheng Kang1, John F Hartwig2

  • 1Department of Chemistry, University of California, Berkeley, CA, USA.

Nature communications
|September 27, 2024
PubMed
概括

研究人员开发了一种新方法,用于将甲基组添加到复杂分子中. 这种技术可以使未激活的C ((sp3) -H键的晚期,无定向甲基化,有助于药物发现和探索"神奇甲基"效应.

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