在环境,技术和医学中的微生物细胞外聚合物质
Hans-Curt Flemming1,2, Eric D van Hullebusch3, Brenda J Little4
1Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore, Singapore. hc.flemming@uni-due.de.
Nature reviews. Microbiology
|September 27, 2024
概括
细胞外聚合物物质 (EPS) 在微生物生物膜中形成保护基质,影响它们在各种环境中的相互作用和作用. 本综述探讨了EPS在自然,技术和医学中的多方面的功能.
科学领域:
- 微生物学 微生物学
- 环境科学 环境科学
- 生物技术是生物技术.
背景情况:
- 微生物生物膜被包裹在由细胞外聚合物 (EPS) 组成的自我生产的矩阵中,包括多糖,蛋白质,细胞外DNA和脂质.
- 在自然生态系统 (土壤,沉积物,海洋息地) 和技术系统 (废水处理,水分配) 中,EPS起着至关重要的作用,有助于生物和腐蚀.
- 在医学中,EPS保护病原体免受宿主防御和抗微生物药物的影响,并可能作为毒性因子.
研究的目的:
- 审查微生物生物膜中细胞外聚合物质 (EPS) 的多样性功能.
- 探索EPS在环境,技术和医疗环境中的意义.
- 突出EPS作为生物膜在各种应用中的关键功能组件.
主要方法:
- 关于微生物生物膜和EPS的科学研究的文献综述.
- 综合有关EPS组成,特性和功能的信息.
- 在自然,技术和医疗环境中EPS角色的分类.
主要成果:
- EPS促进细胞粘附,矩阵凝聚,以及与其他细胞和污染物相互作用.
- 在技术环境中,EPS有助于生物污染和微生物影响的腐蚀.
- 环保纤维保护医疗生物膜中的病原体,并具有潜在的应用,例如在自修复混凝土中.
结论:
- 细胞外聚合物物质 (EPS) 是生物膜的关键功能成分,具有多种影响.
- 了解EPS对于环境,工业和医疗领域的生物膜管理至关重要.
- 环境污染物既带来挑战 (如生物污染,毒性),也带来机遇 (如生物材料).
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