在中国老龄化人口中结核病负担的时间趋势:从GBD 2019的二次数据分析
Beibei Che1,2, Xubin Zheng3, Bin Chen4
1Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200032, People's Republic of China.
BMC pulmonary medicine
|September 28, 2024
概括
在中国老龄化人口中,结核病 (TB) 的负担是显著的,特别是在老年人中. 有针对性的干预措施对于改善这种脆弱群体的病例发现和医疗保健质量至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 老年学是一门学科.
背景情况:
- 由于人口快速老龄化,中国在打击结核病方面面临重大挑战.
- 解决结核病疫情需要了解其在老年人群中的具体负担.
研究的目的:
- 分析1990年至2019年中国结核病发病率,死亡率和DALYs的时间趋势.
- 评估年龄,月经和出生队列对结核病负担的影响,重点关注老年人群.
主要方法:
- 利用了2019年全球疾病负担研究对艾滋病毒阴性个体的数据.
- 用员工结合点回归来计算跨年龄组结核病负担的年平均百分比变化 (AAPC).
- 应用年龄-周期-队列 (APC) 模型来评估发病率和死亡率趋势以及相对风险 (RR).
主要成果:
- 2019年,结核病死亡率和DALY最高的群体集中在70-74岁的年龄组.
- 60岁及以上结核病患者的比例从1990年的23.82%增加到2019年的37.54%.
- 虽然整体结核病死亡率和DALYs下降,但年龄效应显示8589岁组的死亡率增加 (RR=4.59).
结论:
- 结核病给中国老年人带来了相当大的健康负担.
- 加强病例检测策略和提高结核病医疗保健质量对于这一高风险人口群体至关重要.
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