通过在接受阿片类药物使用障碍药物治疗的患者中,通过流行病诱导的隔离来检查疼痛干扰的变化:二次数据分析
Tessa Frohe1, Tim Janssen2, Bryan R Garner3
1Department of Psychiatry & Behavioral Sciences, School of Medicine, University of Washington, 1959 NE Pacific ST, Box 357238, Seattle, WA, 98195-7238, USA.
BMC public health
|September 28, 2024
概括
流行病引起的隔离部分介导了服用阿片类药物使用障碍 (MOUD) 药物的患者疼痛干扰的变化. 疫情前更高的疼痛和阿片类药物使用预测了更大的隔离,这反过来影响了疼痛水平.
科学领域:
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
- 疼痛医学 医学 疼痛医学
背景情况:
- 在美国,COVID-19大流行加剧了阿片类药物使用,社会隔离和疼痛干扰.
- 接受阿片类药物使用障碍 (MOUD) 药物治疗的患者经常报告高疼痛水平.
- 疫情为研究阿片类药物使用,疼痛和孤立在这个弱势群体中的相互作用提供了独特的背景.
研究的目的:
- 调查疫情引起的社会隔离是否会影响MOUD患者疼痛干扰的变化.
- 检查大流行前阿片类药物使用,疼痛干扰和与大流行相关的隔离之间的关系.
- 为了为经历疼痛和孤立的MOUD个体提供有针对性的干预信息.
主要方法:
- 分析了来自一个集群随机试验的数据,该试验涉及188名在八个治疗方案中接受MOUD的患者.
- 收集了大流行前关于疼痛干扰和阿片类药物使用的数据.
- 一项补充调查评估了2020年5月至6月期间的流行病诱导的隔离 (n=133,71%的响应率),随后进行了流行病时代疼痛和阿片类药物使用的评估.
主要成果:
- 流行病引起的隔离部分介导了MOUD患者疼痛干扰的变化.
- 流行病前更高的疼痛干扰和阿片类药物使用与流行病引起的隔离增加有显著的关联.
- 流行前的疼痛干扰预测了流行性疼痛干扰,隔离部分解释了这种关系.
结论:
- 在MOUD患者中,患有更高的流行前疼痛和阿片类药物使用的患者在社交距离期间报告了更大的隔离.
- 这种隔离部分解释了观察到的疼痛干扰变化.
- 促进社会联系的干预措施可以减少疼痛干扰并改善MOUD患者的生活质量.
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