瘤性ACSM6在膀癌中损害了CD8+ T细胞基础的免疫反应
Zhenyu Nie1,2, Bolong Liu1,3, Jinhui Liu1,2
1Department of Urology, Xiangya Hospital, Central South University, Changsha, China.
Biomarker research
|September 28, 2024
概括
ACSM6是一种膀癌瘤基因,驱动瘤生长和入侵. 它还抑制了CD8+T细胞的活动,创造了一个非炎症性瘤环境,并预测了免疫治疗反应不佳.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 分子生物学分子生物学
背景情况:
- 膀癌免疫疗法面临由于治疗耐药性的挑战.
- 鉴定出ACSM6是一种在膀癌中过度表达的瘤基因.
- 了解ACSM6的作用对于改善膀癌治疗至关重要.
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