评估患有炎症性肠病的儿童的生长情况
1Department of Pediatrics, Faculty of Medicine, Marmara University, Istanbul 34899, Türkiye.
Children (Basel, Switzerland)
|September 28, 2024
概括
患有克罗恩病的儿童在两年内显著改善了生长. 监测生长参数对于儿童患者的炎症性肠病 (IBD) 管理至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 炎症性肠道疾病研究研究
- 儿童成长与发展 儿童成长与发展
背景情况:
- 炎症性肠病 (IBD) 包括克罗恩病 (CD) 和性结肠炎 (UC),显著影响儿童的健康.
- 增长障碍是儿科IBD的常见并发症,需要仔细监测和管理.
- 了解生长参数的变化对于评估儿科IBD的疾病活性和治疗疗效至关重要.
研究的目的:
- 评估诊断为IBD的儿童的人类测量和生长z-score的变化.
- 为了比较克罗恩病和性结肠炎的儿科患者之间的生长轨迹.
- 评估定期增长参数监测对优化儿科IBD治疗结果的有用性.
主要方法:
- 对2010-2018年IBD患者数据的回顾性审查.
- 在诊断和1/2年随访时收集人体测量 (身高,体重,BMI) 和临床/实验室数据.
- 计算体重与年龄,身高与年龄,BMI与年龄和生长速度的z-score来评估生长.
主要成果:
- 儿童克罗恩病患者在两年内观察到体重相对于年龄,身高相对于年龄和BMI相对于年龄的z-score显著增加 (p <0.05).
- 与CD患者的第一年相比,第二年增长速度z-score显著增加 (p < 0.001).
- 在随访期间,小儿性结肠炎患者的体重与年龄,身高与年龄或BMI与年龄的z-score没有显著改善.
结论:
- 儿科IBD患者在两年随访后表现出改善的生长参数,特别是克罗恩病患者.
- 与临床和实验室标记一起,对人类测量测量的定期监测对于评估治疗反应至关重要.
- 优化IBD儿童的生长需要对他们的状况进行持续的监测和管理.
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